Abraxane Drug Interactions

When rifamycin antibiotics, "live" vaccinations, or certain anticonvulsants are taken together with Abraxane, drug interactions may occur. These reactions may affect the level of Abraxane in your blood, which can increase your risk of developing side effects or decrease the effectiveness of the medicine. To ensure your safety, tell your healthcare provider about any other medications you are taking.

An Overview of Interactions With Abraxane

 Abraxane® (protein-bound paclitaxel) can potentially interact with other medications. Some of these medicines that may lead to interactions with Abraxane include:
 
  • Certain antibiotics or antifungals, including:

 

    • Clarithromycin (Biaxin®)
    • Erythromycin (Ery-Tab®)
    • Isoniazid (Nydrazid®)
    • Itraconazole (Sporanox®)
    • Ketoconazole (Nizoral®)
    • Miconazole
    • Telithromycin (Ketek®)

 

  • Certain anticonvulsants, including:

 

 

  • "Live" vaccinations, including:

 

 

  • Rifamycin antibiotics, including rifabutin (Mycobutin®), rifampin (Rifadin®), and rifapentine (Priftin®).
     
Abraxane Drug Interactions Article Continues on Next Page >
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD
 
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