Adriamycin Drug Interactions

If certain medications are taken with Adriamycin, drug interactions can occur. Among the drugs that can potentially interact with Adriamycin are "live" vaccinations, cyclophosphamide, paclitaxel, and trastuzumab. Some of these drug interactions with Adriamycin can increase your risk of congestive heart failure or dangerous side effects, such as seizures and problems with bone marrow and blood cells.

 

An Overview of Adriamycin Drug Interactions

Adriamycin® (doxorubicin hydrochloride) can potentially interact with other medications. Some of these medicines that may lead to Adriamycin interactions include:
 
  • Cyclophosphamide (Cytoxan®, Neosar®)
  • Cyclosporine (Gengraf®, Neoral®, Sandimmune®)
  • Cytarabine (Cytosar-U®)
  • "Live" vaccinations, including:
o Chickenpox vaccine (varicella vaccine)
o FluMist® (the nasal vaccine for influenza; the injected vaccine is not "live")
o MMR vaccine (measles, mumps, rubella vaccine)
o Smallpox vaccine
o BCG vaccine (used in some countries for tuberculosis) 
(Adriamycin Drug Interactions Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;