For Paget's disease treatment, the recommended Aredia dosage is 30 mg daily for three days. When used to prevent bone problems due to multiple myeloma, the usual dosage is 90 mg once a month. For breast cancer that has spread to bones, the recommended dosage is 90 mg every three to four weeks. Aredia dosing for high blood calcium varies from 60 to 90 mg.
The dose of Aredia® (pamidronate disodium) that your healthcare provider recommends will vary depending on a number of factors, including:
- How well your kidneys are functioning
- The condition being treated
- Other medications you may be taking
- Other medical conditions you may have.
As always, do not adjust your Aredia dose unless your healthcare provider specifically instructs you to do so.
The recommended Aredia dose for treating high blood calcium due to cancer (known medically as hypercalcemia of malignancy) is 60 to 90 mg as a single dose, depending on the severity of your hypercalcemia. The dose should be given by IV over 2 to 24 hours. Giving the dose over shorter periods of time may increase the risk of kidney damage. While many people will respond after just one dose, a second dose may be necessary. In this case, the second dose should be given at least a week after the first dose (to give the first dose a chance to work).
The recommended Aredia dose for treating Paget's disease of bone is 30 mg daily for three days in a row. The doses should be given by IV and should take four hours for each dose. Most studies of Aredia for Paget's disease used just a single dose of the drug. However, your healthcare provider may recommend re-treatment with Aredia if necessary.