When and How to Take Cyclophosphamide

Some general considerations for when and how to take this medication include:
  • Cyclophosphamide comes in two forms: a tablet that is taken by mouth and an injection given through an IV. Some people take cyclophosphamide every day, while others take it intermittently.
  • Try to take cyclophosphamide tablets on an empty stomach if possible. If the drug upsets your stomach too much, try taking it with food.
  • In general, it is usually best to take cyclophosphamide tablets in the morning or afternoon. Taking them at night may increase your risk of bladder damage. Your healthcare provider may also recommend drinking large amounts of water to flush your bladder out and protect it from damage.
  • For the injectable form, most people receive their cyclophosphamide injection at a healthcare provider's office, a hospital, or an "infusion center."
  • For the medication to work properly, it must be taken as prescribed. It will not work as well if you stop taking it before your healthcare provider recommends.

Dosing Information

The dosage that your healthcare provider recommends will vary depending on a number of factors, including:
  • Whether you are taking cyclophosphamide tablets or the injection form of the medicine
  • The type of cancer being treated
  • Your height and weight
  • Other medications you may be taking
  • Other medical conditions you may have.
As always, do not adjust your cyclophosphamide dose unless your healthcare provider specifically instructs you to do so.
(Click Cyclophosphamide Dosing for more information.)
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