Drug Interactions With Cyclophosphamide

A number of medications may potentially cause drug interactions with cyclophosphamide. Some of these drugs include rifamycin antibiotics, "live" vaccinations, and certain anticonvulsants. When these cyclophosphamide drug interactions occur, the level of cyclophosphamide in your blood may be increased and you may be at a higher risk of side effects.

 

An Overview of Drug Interactions With Cyclophosphamide

Cyclophosphamide (Cytoxan®) can potentially interact with certain other medications. Some of these medicines that may lead to cyclophosphamide drug interactions include:
 
  • Anthracycline chemotherapy medications, including:

 

 

  • Certain anticonvulsants, including:

 

 

  • "Live" vaccinations, including:

 

 

  • Rifamycin antibiotics, including rifabutin (Mycobutin®), rifampin (Rifadin®), and rifapentine (Priftin®).
     
(Drug Interactions With Cyclophosphamide Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;