Docefrez and Pregnancy

When studied in pregnant animals, Docefrez appeared to cause miscarriages, reduced fetal weights, and bone defects. Due to the potential risks, this drug is classified as a pregnancy Category D medicine, meaning it is generally not recommended for use during pregnancy. However, a healthcare provider may prescribe it if the benefits outweigh the risks.

Can Pregnant Women Receive Docefrez?

Docefrez™ (docetaxel) is a prescription medication used to treat various types of cancer. Based on the results of animal studies, this drug may cause harm to an unborn child if used during pregnancy.
 

What Is Pregnancy Category D?

The U.S. Food and Drug Administration (FDA) uses a category system to classify the possible risks to a fetus when a specific medicine is taken during pregnancy. Docefrez is classified as a pregnancy Category D medication.
 
Pregnancy Category D is a classification given to medicines that have been shown to present a risk to the fetus in studies of pregnant women but may still offer benefits that outweigh the risks the drug presents. A pregnancy Category D medicine may still be given to a pregnant woman if the healthcare provider believes that the benefits to the woman outweigh the possible risks to the unborn child.
 
Docefrez has not been adequately studied in pregnant women. However, it has been studied in animals. When this drug was given to pregnant rats and rabbits, it appeared to cause several problems, including miscarriage, reduced fetal weight, and bone defects. These problems occurred even at very small doses.
 
In general, Docefrez is not recommended for use in pregnant women. However, because cancer is potentially fatal, a healthcare provider may recommend using Docefrez in a pregnant woman if safer treatments are not an option.
 
Women of childbearing potential should use an effective form of birth control during Docefrez treatment to prevent pregnancy. If you are a woman of childbearing potential, please speak with your healthcare provider about the best birth control options for your particular situation.
 
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