Docefrez Side Effects

Swelling, hair loss, and weakness were some of the most commonly reported side effects when Docefrez was given to people during clinical trials. Research also showed that this chemotherapy medication can cause potentially dangerous reactions. Notify your healthcare provider immediately if you develop serious complications, such as painful urination, severe vomiting, or unexplained swelling, as these may require medical treatment.

An Introduction to Docefrez Side Effects

Just like any chemotherapy medicine, Docefrez™ (docetaxel) can cause side effects, some of which can be significant. Although not everyone who receives the medication will have problems, most people will experience some type of side effect during treatment. Talk to your healthcare provider about ways to prevent or manage adverse reactions.
(This article covers many, but not all, of the possible side effects with Docefrez. Your healthcare provider can discuss a more complete list with you.)

Common Side Effects With Docefrez

Docefrez has been studied extensively in clinical trials. In these studies, the side effects that occurred in a group of people receiving Docefrez were carefully documented and (in some trials) compared to the side effects that occurred in a group of people receiving a different chemotherapy medication. As a result, it was possible to see what side effects occurred, how often they appeared, and how they compared to the other medication.
In these studies, the most common Docefrez side effects included:
  • Neutropenia (a low level of a type of white blood cell known as neutrophils) -- in up to 99 percent of people
  • Leukopenia (a low level of a type of white blood cell known as leukocytes) -- up to 99 percent
  • Anemia (low level of red blood cells) -- up to 94 percent
  • Hair loss (alopecia) -- up to 76 percent
  • Fluid retention (swelling, usually of the arms, hands, legs, ankles, or feet) -- up to 67 percent
  • Weakness or lack of energy -- up to 66 percent
  • Burning, tingling, numbness, or pricking sensations in the hands or feet -- up to 58 percent
  • Skin reactions, such as redness, itching, peeling, or blisters on the skin -- up to 54 percent
  • Mouth or lip sores -- up to 52 percent.
Other common side effects, occurring in 4 percent to 43 percent of people, included:
  • Diarrhea (see Chemotherapy-Induced Diarrhea)
  • Nausea (see Chemotherapy and Nausea)
  • Fever
  • Fingernail or toenail changes, including changes in color or separation of the nail from the nail bed (see Skin and Nail Problems With Chemotherapy)
  • Infections
  • Vomiting
  • Muscle and joint pain
  • An excess tearing
  • An allergic reaction
  • Low level of platelets in the blood, which could increase the risk for bleeding
  • Increases in liver enzymes, which could be a sign of liver problems
  • Infusion reactions (an allergic-type reaction that occurs during the injection).
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Docefrez Chemotherapy Information

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