Femara® (letrozole) -- a medication used to treat breast cancer in postmenopausal women -- is generally safe and well tolerated. However, this does not mean that Femara is free from risk. Side effects are possible (which is true for all medicines), and some people may not be able to take this drug.
In clinical trials, for example, commonly reported side effects of Femara included hot flashes, fatigue, and joint pain. While these are often mild and easily treated, there is risk of potentially serious reactions with this drug, such as unexplained vaginal bleeding, blood clots, or the appearance of new tumors.
To minimize your risk of problems with Femara, tell your healthcare provider about any other medical conditions you have. If you have liver disease or osteoporosis, for example, your healthcare provider may want to use a different medication instead.
(To learn more about the risks associated with this drug, click Femara Side Effects and Femara Warnings and Precautions. These articles also talk about how to ensure your safety during treatment and what to do if side effects occur.)