Drug Interactions With Goserelin Acetate Implant

If certain diabetes medicines are used in combination with goserelin acetate implants, there is a possibility for drug interactions. Some of these reactions can decrease the effectiveness of the diabetes medicines. Your healthcare provider may recommend that you check your blood sugar levels more often, and he or she may need to adjust your dosages of the diabetes medications.

An Overview of Goserelin Acetate Implant Interactions

The
 goserelin acetate implant (Zoladex®) is a prescription medication used in the treatment of certain gynecological conditions, as well as prostate and breast cancers. It belongs to a class of drugs called gonadotropin-releasing hormone (GnRH) agonists.
 
The goserelin acetate implant may cause negative interactions when combined with certain drugs used to treat diabetes. Some of these diabetes medications may include:
 
  • Alpha-glucosidase inhibitors, such as:
 
 
  • Bromocriptine (Cycloset™)
  • Dipeptidyl peptidase-4 (DPP-4) inhibitors and combination DPP-4 medications, such as:
 
 
  • Glitazones and glitazone combination medications, such as:
 
 
  • Glucagon-like peptide 1 receptor agonists, such as:
 
 
  • Insulin of any type
  • Meglitinides, such as:
 
 
 
 
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Written by/reviewed by: Susan Lakey, PharmD, MPH
Last reviewed by: Kristi Monson, PharmD
 
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