Goserelin Acetate Implant

How Does It Work?

The goserelin acetate implant belongs to a group of medicines called gonadotropin-releasing hormone (GnRH) agonists. GnRH is a hormone found naturally in the body. It controls the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from the pituitary gland (a tiny gland located beneath the brain). LH and FSH stimulate the production of testosterone in the testes and estrogen in the ovaries.
The goserelin acetate implant acts like GnRH, stimulating the production of LH and FSH. However, after several weeks, the implant overstimulates the pituitary gland and it stops making these hormones. As a result, there is a decrease in levels of testosterone and estrogen. This decrease is responsible for the beneficial effects of goserelin acetate implants.
This medication comes as a tiny implant that is injected beneath the skin of the abdomen (stomach). The implant slowly releases the drug as it dissolves over a period of 4 to 12 weeks (depending on the strength of the implant being used).

When and How to Use This Medicine

Some general considerations to keep in mind during treatment with the goserelin acetate implant include the following:
  • This medication is given as a tiny implant that is injected just beneath the skin (subcutaneously) on the abdomen (stomach) every 4 or 12 weeks. Make sure you know how often you should receive your implant.
  • A healthcare provider will administer the injection in a healthcare setting.
  • The implant will dissolve in your body over time; it does not need to be removed.
  • For this drug to work properly, it must be used as prescribed. Your symptoms may return if you miss a dose.
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Goserelin Acetate Implant Information

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