Herceptin Indications

Adults who have certain
 types of breast cancer or stomach cancer may be prescribed the drug Herceptin® (trastuzumab). The specific indications (or uses) for Herceptin include treating breast cancer in the following ways:
 
  • In combination with chemotherapy to prevent cancer from returning after breast cancer surgery for node-positive cancers (that have spread to lymph nodes).
     
  • Alone to treat people who have already undergone chemotherapy for metastatic breast cancers (that have spread to other parts of the body).
     
  • In combination with paclitaxel (Onxol®, Taxol®) to treat metastatic breast cancers in people who have not had prior chemotherapy.
     
Herceptin is approved to treat stomach cancer only when used in combination with chemotherapy. Specifically, it is approved to be used in combination with cisplatin (Platinol®) and either capecitabine (Xeloda®) or 5-fluorouracil (5-FU).
 
This medication is not approved for use in children or adolescents, and there are currently no off-label (unapproved) uses for Herceptin.
 
(To learn more about the possible indications for this drug, click Herceptin Uses. This article provides more information on how this medicine works and provides a detailed explanation of breast cancer.)
 
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD