Breast Cancer Home > Aredia and Insomnia

There are many potential side effects of Aredia, and insomnia appears to be one of them. Up to 25.1 percent of people taking the drug developed insomnia during clinical studies. Improving sleep habits is often the best cure for insomnia. If you are taking Aredia and insomnia occurs, contact your healthcare provider so he or she can recommend tips for improving sleep.

Aredia and Insomnia: An Introduction

Insomnia is a common side effect of Aredia® (pamidronate disodium). In clinical studies, up to 25.1 percent of people taking Aredia experienced insomnia. However, almost as many people (up to 19.4 percent) not taking Aredia also experienced insomnia. The risk of insomnia seemed to increase with a higher Aredia dosage.

What Is Insomnia?

People with insomnia have one or more of the following insomnia symptoms:
  • Difficulty falling asleep
  • Waking up often during the night and having trouble going back to sleep
  • Waking up too early in the morning
  • Non-refreshing sleep.

Aredia and Insomnia: Suggestions

In many cases of insomnia due to Aredia, simply improving sleep habits can be very helpful. Some tips for better sleep include:
  • Keep a regular sleep-wake cycle. Try to go to bed and wake up at the same time every day.
  • Avoid caffeine, alcohol, and nicotine in the four to six hours before bedtime.
  • Don't exercise within two hours of bedtime. Exercising five or six hours before bedtime may help you sleep more soundly.
  • Don't eat large meals within two hours of bedtime.
  • Don't nap later than 3 p.m.
  • Sleep in a dark, quiet room with a comfortable temperature.
  • If you can't fall asleep within 20 minutes, do a quiet activity somewhere else and return to bed when you're sleepy.
  • Wind down in the 30 minutes before bedtime with a relaxing pre-sleep ritual such as a warm bath, soft music, or reading.
(Click Good Sleep Habits for more suggestions.)
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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