Breast Cancer Home > Perjeta Uses

How Does It Work?

Perjeta is part of a group of medications called monoclonal antibodies. Monoclonal antibodies are used to treat a wide variety of conditions, including cancer.
Perjeta is a special type of monoclonal antibody that is designed to bind to HER2, a protein on the outside of certain cancer cells. When Perjeta binds to HER2 receptor proteins, it has several effects. It may interfere with the cancer cells' ability to grow and multiply. By binding to the HER2 receptor, Perjeta may also serve as a signal to the immune system, which can help destroy the cancer cells.
Perjeta is not a form of chemotherapy. It is less "toxic" than chemotherapy, as it specifically targets the HER2 receptors. Because Perjeta is only prescribed to treat cancers that have a high concentration of HER2 receptors, it targets the tumors, having less of an effect on healthy, noncancerous cells.

Is It Safe for Children to Use Perjeta?

Perjeta is not approved to treat breast cancer in children or adolescents. Talk to your healthcare provider about the benefits and risks of using Perjeta in children or adolescents.

Are There Off-Label Uses?

On occasion, your healthcare provider may recommend this medication for something other than the officially approved uses. This is called an "off-label" use. Using Perjeta for the treatment of HER2-positive stomach cancer would be an off-label use.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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