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Serious Tamoxifen Side Effects
Some side effects with tamoxifen, while occurring infrequently, are potentially serious and should be reported immediately to your healthcare provider. These include, but are not limited to:- Increase in tumor size or appearance of new tumors
- Difficulty breathing
- Depression (see Tamoxifen and Depression)
- Unusual or unexplained vaginal bleeding
- High blood pressure (hypertension)
- Chest pain
- Osteoporosis or broken bones
- Signs of a blood clot, such as:
- Pain
- Swelling
- Tenderness (especially in the legs)
- Signs of an allergic reaction, including:
- Unexplained rash
- Hives
- Itching
- Unexplained swelling.