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- Liver disease, such as hepatitis, cirrhosis, or liver failure
- Kidney disease, such as kidney failure (renal failure)
- Bone marrow depression (when the bone marrow does not make adequate amounts of blood cells) or bone marrow disease
- Any other allergies, including to foods, dyes, or preservatives.
- Pregnant or thinking of becoming pregnant (see Thioplex and Pregnancy)
- Breastfeeding (see Thioplex and Breastfeeding).