Breast Cancer Home > Xeloda Side Effects
Commonly reported side effects of Xeloda include anemia, diarrhea, and nausea. These problems are typically minor, however, and easily treated. Serious side effects, while less common, should be reported immediately to your healthcare provider. These include signs of an allergic reaction, an increase in tumor size, signs of a blood clot, and depression.
An Introduction to Xeloda Side EffectsAs with any medicine, side effects are possible with Xeloda® (capecitabine). However, not everyone who takes the medication will experience side effects. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are easily treated by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with Xeloda. Your healthcare provider can discuss a more complete list of Xeloda side effects with you.)
Common Side Effects of XelodaXeloda has been studied thoroughly in clinical trials, in which the side effects of a group of people taking the drug are documented. In these studies, the most common side effects of Xeloda included:
- Anemia -- in up to 80 percent of people (see Chemotherapy and Anemia)
- Hand-and-foot syndrome (redness and tenderness of the palms and soles) -- up to 60 percent
- Diarrhea -- up to 55 percent (see Chemotherapy-Induced Diarrhea)
- Nausea -- up to 53 percent (see Chemotherapy and Nausea)
- Fatigue or weakness -- up to 42 percent (see Chemotherapy and Fatigue)
- Vomiting -- up to 37 percent
- Abdominal pain (stomach pain) -- up to 35 percent
- Loss of appetite -- up to 26 percent
- Neutropenia (low levels of a certain type of white blood cell) -- up to 26 percent
- Mouth sores -- up to 25 percent (see Mouth and Gum Problems During Chemotherapy)
- Unusual sensations (such as burning or tingling) in the hands or feet -- up to 21 percent (see Nerve and Muscle Problems During Chemotherapy).
Other common side effects (occurring in 5 to 18 percent of people) included:
- Constipation (see Constipation With Chemotherapy)
- Eye irritation, vision changes, or conjunctivitis ("pink eye")
- Difficulty breathing
- Pain, including back pain, muscle pain, or joint pain (see Chemotherapy-Related Pain)
- Indigestion or heartburn
- Insomnia (see Xeloda and Insomnia)
- Hair loss (see Xeloda and Hair Loss)
- Taste changes
- Mood changes.