Drug Interactions With Tamoxifen

Oral Contraceptives
Oral contraceptives may also decrease the effectiveness of tamoxifen and should not be taken with it. Talk to your healthcare provider about alternative birth control methods you can use.
 
Rifamycin Antibiotics
Taking tamoxifen with rifamycin antibiotics may decrease the level of tamoxifen in your blood, perhaps making it less effective. Your healthcare provider may need to increase your tamoxifen dosage to prevent this interaction from occurring.
 
Warfarin
Taking warfarin with tamoxifen can increase your risk of bleeding. Your healthcare provider should monitor you more closely under these circumstances, especially when you are starting or stopping tamoxifen. The manufacturer of tamoxifen states that people taking anticoagulants (including warfarin) should not take tamoxifen.
 

Final Thoughts on Drug Interactions With Tamoxifen

It is possible that not all drug interactions with tamoxifen were discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about any specific interactions that may apply to you.
 
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