Tamoxifen Drug Class

Tamoxifen citrate (Nolvadex®) is prescribed for the treatment and prevention of breast cancer. As part of a class of drugs called selective estrogen receptor modulators (SERMs), tamoxifen works by binding to estrogen receptors in the breast, preventing estrogen from binding. By decreasing these effects of estrogen, the drug can help decrease the growth of breast cancer.
SERMs, including tamoxifen, have both estrogenic (estrogen-like) effects and anti-estrogenic effects. Tamoxifen has anti-estrogenic effects on the breasts, while it has estrogen-like effects on bones, helping to strengthen them.
(For more information, click What Is Tamoxifen Used For?. This article offers more details on the uses of this medication, including off-label uses, and discusses the drug's use in children.)
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