Tamoxifen citrate (Nolvadex®) is a medication licensed for the treatment and prevention of breast cancer. Although it is generally a safe medication, tamoxifen does pose certain risks.
Tamoxifen belongs to a class of drugs known as selective estrogen receptor modulators (SERMs). It's important to note that certain problems can develop in people taking this medication. For example, tamoxifen can increase your risk for certain complications, such as a blood clot, stroke, eye problems, liver problems, or uterine cancer.
Other safety issues that may be a concern in people using tamoxifen include side effects, such as nausea, hot flashes, and vaginal discharge. Also, you may not be able to safely use this medication if you have had a blood clot or if you are taking an anticoagulant ("blood thinner") medication.
(Click Tamoxifen Side Effects and Precautions and Warnings With Tamoxifen for more safety information. These articles offer detailed drug warnings on things like allergic reactions, serious side effects, and more.)